Comparisoft

Best Inventory Management Software for Veterinary Clinics in 2026

Veterinary inventory is among the most regulated in healthcare. Controlled substances require DEA-compliant logs with quantity reconciliation. Vaccines need cold chain documentation and expiration tracking. Pharmaceuticals carry DEA schedules and withholding periods. Beyond compliance, veterinary clinics carry a wide product mix: prescription medications, OTC drugs, biologicals, surgical supplies, retail pet food and accessories, and in-hospital consumables. Getting inventory right protects the practice from regulatory risk while directly improving clinical efficiency — a technician who can't find a drug mid-procedure is a problem no one wants.

Last updated: 2026-04-23

#1

Cornerstone by IDEXX

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Comprehensive veterinary practice management software with integrated inventory management and DEA controlled substance tracking.

Why it fits this industry

Cornerstone is one of the most widely adopted veterinary practice management systems, and its inventory module is built around veterinary-specific workflows: controlled substance logs that meet DEA requirements, vaccine lot and expiration tracking, and automatic inventory depletion when medications are dispensed or administered in a patient record.

Pros

  • DEA-compliant controlled substance tracking and logs
  • Vaccine lot number and expiration date recording
  • Automatic depletion from patient records on dispensing
  • Integrated with IDEXX diagnostic services and lab results

Cons

  • Expensive — full platform cost is significant for small clinics
  • Desktop-based architecture limits remote access
  • Interface shows age compared to cloud-native alternatives

Pricing: Contact for pricing (typically $600-$1,500+/month)

Best for established veterinary clinics and hospitals that want industry-standard practice management with deep, compliance-ready inventory tracking.

Cloud-native veterinary practice management software with integrated inventory, controlled substance management, and reporting.

Why it fits this industry

ezyVet is a fully cloud-based alternative to legacy veterinary systems. Its inventory module handles medication stock levels, controlled substance reconciliation, product dispensing tied to patient records, and reorder point alerts. Accessible from any browser, it suits multi-doctor clinics and specialty hospitals that need reliable remote access.

Pros

  • Fully cloud-based with no local server requirement
  • Controlled substance audit logs included
  • Inventory depletion linked to clinical record dispensing
  • Strong multi-location support

Cons

  • Transition from legacy systems requires significant migration effort
  • Pricing is at the higher end of cloud veterinary platforms
  • Some advanced inventory features require additional configuration

Pricing: Contact for pricing

Best for progressive veterinary clinics and hospitals ready to move to cloud infrastructure and needing compliant inventory management throughout.

#3

Impromed (Covetrus)

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Veterinary practice management software with inventory management, controlled substance tracking, and Covetrus supply ordering.

Why it fits this industry

Impromed includes strong inventory management features and connects directly to Covetrus's pharmaceutical supply platform for integrated ordering and price management. This combination makes it particularly efficient for clinics that use Covetrus as their primary pharmaceutical supplier, streamlining the order-to-shelf workflow.

Pros

  • Controlled substance log management built in
  • Direct integration with Covetrus pharmaceutical ordering
  • Inventory tied to patient records for automatic depletion
  • Established platform with large veterinary user base

Cons

  • Covetrus integration benefits those who use Covetrus as supplier
  • Desktop-based primary interface
  • Reporting can be cumbersome to customize

Pricing: Contact for pricing

Best for veterinary clinics purchasing primarily through Covetrus that want integrated supply ordering and inventory management in one platform.

#4

Shepherd Veterinary Software

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Modern cloud veterinary practice management platform with inventory management designed for usability.

Why it fits this industry

Shepherd is a newer cloud-native platform built by veterinarians frustrated with legacy systems. Its inventory management includes medication tracking, controlled substance logs, and reorder alerts — presented in a clean, modern interface that reduces training time. It's gaining traction with new practices and those replacing aging desktop systems.

Pros

  • Modern, intuitive interface reduces training burden
  • Built-in controlled substance tracking and logs
  • Cloud-native with mobile-friendly access
  • Strong support from a vet-founded company

Cons

  • Newer platform — ecosystem and integrations still growing
  • Multi-location features less mature than established competitors
  • Some advanced features still in development

Pricing: Contact for pricing

Best for new veterinary practices and those replacing legacy systems that want modern cloud infrastructure with compliance-ready inventory out of the box.

#5

AVImark (Covetrus)

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Long-established veterinary practice management software with comprehensive inventory management for clinics of all sizes.

Why it fits this industry

AVImark has one of the largest installed bases in veterinary medicine and its inventory module covers the full range of clinic needs: controlled drug logs, vaccine tracking, inventory counts, and purchase order management. For clinics with staff who know AVImark deeply, it remains a dependable choice with a wide support ecosystem.

Pros

  • Large installed base with extensive support resources
  • Comprehensive inventory including controlled substance management
  • Vaccine and biological tracking with lot numbers
  • Well-understood by veterinary software vendors and consultants

Cons

  • Older architecture — primarily desktop-based
  • Interface is not modern compared to cloud alternatives
  • Migration to newer platforms is becoming a consideration for many

Pricing: Contact for pricing

Best for established veterinary clinics with staff experienced on AVImark that need reliable, full-featured inventory management without the disruption of a platform change.

Buyer's Guide

Veterinary inventory management must satisfy two audiences: the clinical team who needs drugs and supplies available when patients are on the table, and regulatory compliance officers who need audit-ready controlled substance logs. When evaluating platforms, start with controlled substance management — DEA Schedule II-V drugs require precise log entries with every use, waste, and count. Any platform you select must produce these logs in a format that holds up to a DEA inspection. Next, evaluate vaccine and biological tracking — lot numbers, expiration dates, and cold chain documentation matter for liability and patient safety. Finally, consider how inventory integrates with your pharmaceutical supplier: Cornerstone integrates deeply with IDEXX services, Impromed connects to Covetrus, while cloud-native platforms like ezyVet and Shepherd offer more distributor-neutral flexibility.

Frequently Asked Questions

How do veterinary clinics track controlled substances for DEA compliance?
The DEA requires veterinary clinics to maintain a complete running log for Schedule II-V substances including the date, patient, doctor, quantity used, quantity wasted, witness to waste, and remaining balance. These logs must reconcile with physical counts, which most practices do monthly. Veterinary practice management software with built-in controlled substance modules generates these logs automatically as drugs are administered or dispensed through patient records, reducing the risk of documentation errors.
What's the best way to handle vaccine inventory in a veterinary clinic?
Vaccine inventory requires tracking lot numbers and expiration dates at receiving, proper cold chain storage with temperature logs, and FIFO rotation to use older stock first. Vaccines administered to patients should be recorded with lot number and expiration date in the patient record. Most veterinary practice management systems support this workflow, and it's essential for both regulatory compliance and product liability protection.
Should a veterinary clinic track retail products (food, accessories) in the same system as clinical inventory?
Most veterinary practices manage retail products separately from clinical inventory — either through a POS system at the front desk or within the client billing section of their practice management software. Mixing OTC pet food and accessories with pharmaceutical inventory creates confusion in DEA logs and reorder workflows. Many clinics use the product catalog in their practice management software for retail sales while keeping pharmaceutical inventory tracking in a dedicated clinical module.